Frontiers Acetaminophen: Beyond Pain and Fever Relieving Tylenol's Impact on Glutathione and Liver Damage Here's how to make Tylenol work way better Dose it correctly: 1,000 mg at a time, spaced every 8 hours. Smaller doses don't control pain as well. Take it Is Tylenol Bad for Your Liver or Kidneys? GoodRx g glutamyl cycle. Depletion of glutathione by acetaminophen leads to Download Scientific Diagram Your livers unsung hero: Glutathione , Lets talk about what really happens when you take Tylenol (acetaminophen)., Your liver breaks down acetaminophen through several pathways. One pathway creates