Pathology Outlines Melanotic macule Pigmented Oral Lesions: Clues to Identifying the Potentially Malignant Consultant360 Mystery behind labial and oral melanotic macules: Clinical, dermoscopic and pathological aspects of Laugier Hunziker syndrome ORAL MELANOTIC MACULE (OMM) (Also called focal melanosis labial melanotic macule) A benign, localized, flat pigmented lesion of the oral mucosa Caused by a focal increase in melanin production Labial melanotic macule Oral pathology: Noting a pigmented macule that often presents a diagnostic dilemma Registered Dental Hygienists